Fronie presented with advanced polyneuropathy of both the upper and lower limbs. She had a 5 year history of unhealed
ulcers on the plantar surface of both feet with additional ulcers on the distal aspects of the right toes. She was unable
to walk unaided and experienced moderate to severe pain daily.
Soon after beginning treatments the ulcers began to heal, the pain and numbness decreased and Fronie started walking
around her house without her cane. Her hands are becomming less numb and she notes an increase in strength.
Her foot ulcers continue to heal and Fronie reports gradual improvements with time. She no longer worries that
her ulcers will become infected and has reduced her pain medications.